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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNNB1
All Species:
31.52
Human Site:
Y748
Identified Species:
53.33
UniProt:
P35222
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35222
NP_001091679.1
781
85497
Y748
G
H
H
P
G
A
D
Y
P
V
D
G
L
P
D
Chimpanzee
Pan troglodytes
XP_001137676
774
84747
Y741
G
H
H
P
G
A
D
Y
P
V
D
G
L
P
D
Rhesus Macaque
Macaca mulatta
XP_001115474
511
55731
G487
V
D
G
L
P
D
L
G
H
A
Q
D
L
M
D
Dog
Lupus familis
XP_850439
744
81740
H716
P
L
D
P
L
D
M
H
M
D
M
D
A
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q02248
781
85452
Y748
G
H
H
P
G
A
D
Y
P
V
D
G
L
P
D
Rat
Rattus norvegicus
Q9WU82
781
85436
Y748
G
H
H
P
G
A
D
Y
P
V
D
G
L
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516985
781
85506
Y748
G
H
H
P
G
A
D
Y
P
V
D
G
L
P
D
Chicken
Gallus gallus
NP_990412
781
85420
Y748
G
H
H
P
G
A
D
Y
P
V
D
G
L
P
D
Frog
Xenopus laevis
P26233
781
85431
Y748
G
H
H
P
G
A
D
Y
P
V
D
G
L
P
D
Zebra Danio
Brachydanio rerio
NP_571134
780
85502
Y747
G
H
H
P
G
P
D
Y
P
V
D
G
L
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18824
843
91134
P795
G
G
N
I
G
A
I
P
P
S
G
A
P
T
S
Honey Bee
Apis mellifera
XP_391947
811
88602
D775
G
S
T
Y
G
A
M
D
T
M
D
V
A
H
E
Nematode Worm
Caenorhab. elegans
O44326
678
74493
H654
Y
P
T
N
D
G
G
H
S
E
S
I
N
M
A
Sea Urchin
Strong. purpuratus
NP_001027543
825
89711
P793
G
G
D
F
G
M
D
P
G
L
P
D
M
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
65.4
66.4
N.A.
99.8
99.7
N.A.
99.7
99.3
97.4
97.1
N.A.
65.7
67.6
28.5
67.2
Protein Similarity:
100
99
65.4
77.4
N.A.
99.8
99.7
N.A.
99.8
99.6
99
98.9
N.A.
77.2
80.1
46.4
77.7
P-Site Identity:
100
100
13.3
6.6
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
26.6
26.6
0
20
P-Site Similarity:
100
100
13.3
13.3
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
33.3
40
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
65
0
0
0
8
0
8
15
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
15
0
8
15
65
8
0
8
65
22
0
8
65
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
79
15
8
0
79
8
8
8
8
0
8
58
0
8
0
% G
% His:
0
58
58
0
0
0
0
15
8
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
8
8
0
8
0
0
8
0
0
65
0
0
% L
% Met:
0
0
0
0
0
8
15
0
8
8
8
0
8
15
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
8
0
65
8
8
0
15
65
0
8
0
8
58
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
8
8
8
0
0
0
8
% S
% Thr:
0
0
15
0
0
0
0
0
8
0
0
0
0
8
0
% T
% Val:
8
0
0
0
0
0
0
0
0
58
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
58
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _